Renal impairment in myeloma: negative association with isoelectric point of excreted Bence-Jones protein.
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چکیده
منابع مشابه
Renal impairment in myeloma: negative association with isoelectric point of excreted Bence-Jones protein.
The isoelectric point (pI) of the major form of Bence-Jones protein excreted by 62 patients with myeloma and six with macroglobulinaemia was measured by combining isoelectric focusing with immunoblotting techniques. The distribution of the pI values for both kappa and lambda type proteins was bimodal, most falling in the ranges 5.0-6.0 and 7.0-7.5. Plasma creatinine and creatinine clearance and...
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averaged many times (up to 100 times) a peak of activity could sometimes be observed to correspond with the minimum or the maximum intensity of light, according to the cell type ("off cells" or "on cells," respectively). The shape of the response, however, remained completely chaotic. An example of these results is shown in Fig. 1. Control experiments showed that the response of the retinal gan...
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ژورنال
عنوان ژورنال: Journal of Clinical Pathology
سال: 1989
ISSN: 0021-9746
DOI: 10.1136/jcp.42.1.59